Analgesic dibenz[b,f]oxepins

Details Analgesic dibenz[b,f]oxepins Analgesic dibenz[b,f]oxepins

1983-12-12

1985-01-29

Milestone, Norma S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549354, A61K 31335, C07D31314

Patent

active

044965826

ABSTRACT:
There are described analgesic dibenz[b,f]oxepins having the general formula ##STR1## wherein n is an odd integer 1-7 inclusive; R is --CO.sub.2 R.sub.1 or --CH.sub.2 OR.sub.2 where R.sub.1 is H, C.sub.1-5 lower alkyl, aralkyl, ##STR2## R.sub.3 being C.sub.1-5 lower alkyl; X and Y are each independently hydrogen, halogen, trifluoromethyl, C.sub.1-5 lower alkoxy, C.sub.1-5 lower alkyl, C.sub.1-5 lower alkylthio, or hydroxy; and the dotted line may be a bond or nothing.

REFERENCES:
P. Cagniant et al., C. R. Acad. Sc. Paris, Ser. C, vol. 283 (Dec. 8, 1976), pp. 683-686.

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