Analgesic compounds, extracts containing same and methods of...

Details Analgesic compounds, extracts containing same and methods of... Analgesic compounds, extracts containing same and methods of...

2004-11-26

2009-11-17

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S004400, C536S018100

Reexamination Certificate

active

07618946

ABSTRACT:
Various compounds obtained from plants of theBarringtoniaspecies which are derived from Barringtoside A and Barringtoside C as precursor compounds which especially have an arabinopyranosyl substituent at the 21 position which may optionally be further substituted with benzoyl, dibenzoyl, methyl butanoyl, methyl butyryl or tigloyl at the 3 or 4 positions. Alternatively at the 21 position there is provided tigloyl, benzoyl or dibenzoyl substituents.

REFERENCES:
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The Merck Manual of Diagnosis and Therapy, Seventeenth Edition, Published by Merck Research Laboratories (1999) Beers and Berkow, eds., pp. 1373, 1374, and 1511.
Woolf et al., “Neuropathic pain: aetiology, symptoms, mechanisms, and management” (1999) The Lancet, vol. 353, pp. 1959-1964.
Crublet et al., Acylated triterpenoid saponing from the stem bark of Foetidia africana, Journal of Natural Products (2002), 65 (11), 1560-1567, American Chemical Society, (Abstract).
Wang et al., Triterpenoid saponins from Berneuxia thibetica, Phytochemistry (1998), 48(8), 1411-1414, Elsevier Science Ltd., (Abstract).
Burczyk et al., Saponins from Hacquetia epipactis, Phytochemistry (1995), 39(11), 195-8, Elsevier Science Ltd., (Abstract).
Pal et al., Saponins from Barringtonia acutanglua, Phytochemistry (1994), 35(5), 1315-18, (Abstract).
Kitagawa et al., Structure of desacyl-jegosaponin, a common desacyl derivative of jegosaponin isolated from pericarps of Styrax japonica, Chemical & Pharmaceutical Bulletin (1974), 22(7), 1675-7, (Abstract).

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