Analgesic compositions comprising 1H- or respectively 2H-indazol

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2602475EP, A61K 31535

Patent

active

039819973

ABSTRACT:
A process of producing 1H- or respectively 2H-indazolone-3, particularly 3-(.beta.-morpholino-ethoxy)-1H-indazole, 3-(.gamma.-morpholino-propoxy)-1H-indazole and the novel chemical compound 3-(.beta.-morpholino-ethoxy)-4,5,6,7-tetrahydro-2H-indazole by reacting the enolate of 1H-indazolone-3 with morpholino-ethyl-chloride or respectively with .gamma.-morpholino-propyl-chloride, or by reacting the enolate of 4,5,6,7-tetrahydro-2H-indazolone-3 with .beta.-morpholino-ethyl-chloride, under well-defined conditions, resulting in higher yields and optimum purity.

REFERENCES:
patent: 3318905 (1967-05-01), Palazzo
patent: 3428634 (1969-02-01), Palazzo
patent: 3470194 (1969-09-01), Palazzo

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