Analgesic combination

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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Details

C424S400000

Reexamination Certificate

active

06929805

ABSTRACT:
The present invention relates to medicinal preparations which can be administered orally and contain a fixed combination of at least one locally acting analgesic with a rapid onset of action and at least one systemically acting analgesic with a sustained action.

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Chemical Abstracts, vol. 102, No. 7, 1984; Columbus, Ohio, US; abstract No. 55856, Shibata et al: “Effects of Combinations on Some Anti-Inflammatory Drugs with Lidocaine HCI on Inflammatory Pain” XP002076707 see abstract & Shibata et al: Shika Kiso Igakkai Zasshi, vol. 26, No. 3, 1984, pp. 872-881.
Kagan, et al., J.Int.Med.Res., 1982, 10, 443: “Two Lozenges Containing Benzocaine Assessed in the Relief of Sore Throat”.
Schachtel, et al., Arch.Intern.Med., 1991, 151, 733ff.: “Caffeine as an Analgesic Adjuvant”.
Schachtel, et al., Clin.Pharmacol.Ther., 1988, 44, 704ff: “Sore throat pain in the evaluation of mild analgesics”.
Schachtel, et al., Clin.Pharmacol.Ther., 1994, 55, 464ff.: “A placebo-controlled model to assay the onset of action of nonprescription-strength analgesic drugs”.

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