Analgesic, anti-inflammatory and skeletal muscle relaxant compos

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 3119

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active

049238981

ABSTRACT:
Novel pharmaceutical analgesic, anti-inflammatory and skeletal muscle relaxant compositions and methods of using same comprising an analgesically and anti-inflammatory effective amount of at least one non-steroidal anti-inflammatory drug other than aspirin, acetaminophen and phenacetin, in combination with an effective amount of a skeletal muscle relaxant.

REFERENCES:
patent: 4683243 (1987-07-01), Sunshine et al.
Physicians' Desk Reference, 28th Ed., (1974), p. 972.
Armas & Valencia, "Eficacia terapeutica de la associacion naproxen-carisoprodol en ciertas enfermedader musculoesqueleticas", [Therapeutic Effectiveness of Naproxen-Carisoprodol Association in Certain Musculoskeletal Disorders], in Investigation Medica Interacional, pp. 350-356, (1983), and English translation thereof.
Goti & Valenica, "Caracterizacion clinica de una nueva asociacion (naproxen+carisprodol) en padecimientos del aparato musculoesqueletico", [Clinical Description of a New Association (Naproxen+Carisoprodol) in Ailments of the Musculoskeletal Apparatus], Investigation Medica Internacional, pp. 475-478, (1983), and English translation thereof.
Socialist Republic of Romania Description of Invention 82,717, copy of patent and English translation thereof.
Rego, "Mio-Relaxantes No Tratamento Das Lombalgias Aguda E Da Lombo-Ciaticas Recentes", [Muscle Relaxants in the Treatment of Acute Lumbalgias and Recent Lumbo-Sciatica Cases], Acta Reumatolgica Portuguesa, II, 2:363-364, (1974), copy of the original and English translation thereof.
Schror, "Analgetisch-antiphlogistische Therapie Von Schmerzzustanden des Bewegungsapparates", [Analgesic-Antiphlogistic Therapy of Locomotor System Pain], Therapiewoche, 28, 5657-5663, (1978), copy of the original and English translation thereof.
Schar, "Medikamentose Behandlung von Lumboischialgien", [Drug Treatment of the Lumbago-Sciatic Syndrome], Schweiz. Rundschau Med., (Praxis), vol. 68, No. 5, pp. 141-142, (Jan. 30, 1979), copy of original article and English translation thereof.
Kolodny and Klipper, "Bone and Joint Diseases in the Elderly", Hospital Practice, pp. 91-101, (Nov., 1976).
Nascimento, "Use of an Association Containing an Analgesic, a Muscle Relaxant and Vitamin B Complex in Degenerative Joint Diseases, Extra-Articular Rheumatic Ailments and Traumatic Afflictions", F med (BR), 83(3):361-363, (1981), original article and English translation thereof
Repschlaeger and McPherson, "Classification, Mechanism and Management of Headache", Clinical Pharmacy, vol. 3, pp. 139-150, (Mar.-Apr. 1984).

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