Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-01-06
1996-12-10
Gibson, Sharon
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546124, 546127, 546128, 546129, 546130, A61K 3144, C07D45102
Patent
active
055831427
ABSTRACT:
Compounds of general formula: ##STR1## where: Ar=phenyl or beta-naphtyl, or aromatic heterocyclic 6-membered ring containing one or two nitrogen atoms;
R.sub.1 =one or more substituents of the Ar nucleus, preferably in para position, and selected out of the group consisting of H, CH.sub.3, CH.sub.2 --CH--(CH.sub.3).sub.2, O--CH.sub.3, Cl, F, Br, CF.sub.3, NH.sub.2, S--CH.sub.3, CN, NO.sub.2 R.sub.2 =H, CH.sub.3, C.sub.2 H.sub.5, CH(CH.sub.3).sub.2 ;
R.sub.3 = ##STR2## Where R.sub.4 =H, CH.sub.3, C.sub.2 H.sub.5 R.sub.5 =H, CH.sub.3
X=none O, S, NH, NCH.sub.3, --CH=CH--, --C.ident.C--
Y=O, NH,
both in the racemic Form and in the isomeric enantiomeric forms,
which produce a nootropic effect, i.e. memory enhancement and learning facilitation, as well as an analgesic effect.
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Bartolini Alessandro
Ghelardini Carla
Giotti Alberto
Gualtieri Fulvio
Scapecchi Serena
FIDIA S.p.A.
Gibson Sharon
Kilby Scalzo Catherine
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