Analgesic and anti-inflammatory compositions comprising diphenhy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514567, 514570, A61K 3119, A61K 31195

Patent

active

047555327

ABSTRACT:
Novel pharmaceutical compositions of matter are provided comprising analgesic
on-steroidal anti-inflammatory drugs and diphenhydramine and methods of using said compositions to elicit an enhanced analgesic and/or anti-inflammatory response in mammalian organisms in need of such treatment.

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Rote Liste 1977/78; 71 021 B.
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Cappe, B. E. et al, "Recent Advances in Obstetric Analgesic," JAMA, 1954, 154(5):377-379.
Campos, V. M. et al, "The Analgesic and Hypothermic Effects of Nefopam, Morphine, Aspirin, Diphenhydramine and Placebo", Journal of Clin. Pharmacology, Jan. 1980, pp. 42-49.
Albal, M. V. and Chandorka, A. G., "Clinical Evaluation of Sedyn-a-Forte, an Analgesic Injection Containing Analgin, Diphenhydramine and Diazepam," Indian Journal of Ophthalmology, 1982, 30:271-273.
Beaver, W. T. and Feise, G., "Comparison of the Analgesic Effects of Morphine, Hydroxyzine, and Their Combination in Patents with Postoperative Pain," Advances in Pain Research and Therapy, 1976, 1:553-557.
Bluhm et al, "Potentiation of Opioid Analgesia by H.sub.1 and H.sub.2 Antagonists," Life Sciences, 1982, 31:1229-1232.

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