Analgesic action of substance P

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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2601125R, C07C10352, A61K 3700

Patent

active

040596931

ABSTRACT:
Substance P, an undecapeptide of mammalian origin, and its analogs containing its essential amino acid sequence, are substantially nonaddictive analgesics when administered to mammals such as humans and other warm-blooded animals by intraperitoneal or intramuscular injection in analgesically effective amounts.

REFERENCES:
patent: 3862114 (1975-01-01), Scandrett
patent: 3912711 (1975-10-01), Leeman et al.
Arch. Pharmacol. 285, 301-313 (1974).
Experientia 18, 297-344 (1962).
Arch. Pharmacol. 281, 233-239 (1974).

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