Analgesic 4-carboxy-pyrrolidin-2-one compound

Details Analgesic 4-carboxy-pyrrolidin-2-one compound Analgesic 4-carboxy-pyrrolidin-2-one compound

1982-02-19

1984-10-09

Rollins, Alton D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424274, 424267, 424246, 42424853, 544 584, 544170, 544172, 546216, 546221, 546240, 548550, 548551, 548570, 549231, 549233, 564274, 564275, A61K 3140, C07D207277

Patent

active

044763115

ABSTRACT:
Analgesic and anti-inflammatory compounds are provided. These compounds possess the following general formula: ##STR1## wherein R=--COOR.sub.5, --CH.sub.2 CO.sub.2 H, ##STR2## wherein A and B=hydrogen, lower alkyl, hydroxy alkyl, lower alkyl amine, substituted lower alkyl amine, aminoalkyl, substituted aminoalkyl;

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patent: 4196091 (1980-04-01), Schlicht
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Cushman et al., J. Org. Chem., vol. 37, pp. 1268-1271 (1972).
Leonard et al., J. Am. Chem. Soc., vol. 75, pp. 3727-3730 (1953).
Joannic et al., C. R. Acad. Sc. Paris, Ser. C., vol. 275, pp. 45-48 (1972).

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