Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines

Details Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines

1978-11-29

1981-08-18

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546192, 546236, 546240, 546339, 546344, 546348, 546350, A61K 31445, C07D21122, C07D21114

Patent

active

042846358

ABSTRACT:
4-Phenylpiperidines bearing substituents at the 1,2,4 and 5-positions are potent analgesics. Pharmaceutical formulations containing such compounds and a method for effecting analgesia are provided.

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McElvain, S. et al., J. Am. Chem. Soc., 80, 3915 (1958).
Kugita, H., et al., J. Med. Chem., 8, 313 (1965).
Jacoby, R., et al., J. Med. Chem., 17, 453 (1974).
Kugita, H., et al., J. Med. Chem., 7, 298 (1964).

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