Anaesthetic steroids of the androstance and pregnane series

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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26023955C, 2603971, 2603974, 26039745, 424243, C07J 500

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active

039534294

ABSTRACT:
Steroids of the androstane and pregnane series possessing a 2.alpha.-hydrogen or halogen or an alkyl group; a 3.alpha.-hydroxy or acyloxy group, a 3.beta.-hydrogen or alkyl group; an 11.beta.-hydrogen or hydroxy group or an epoxy group linked also to the 9-position; an 11.alpha.-hydrogen or alkyl or allyl group; or an 11-oxo group; a 16 hydrogen or halogen or a methyl or dimethyl group; a 20-oxo or ethylenedioxy group; and a 20-methyl or alkoxy group. The compounds may be unsaturated at the 1(2), 8(9) or 9(11) positions.
The compounds possess anaesthetic properties.

REFERENCES:
patent: 3048606 (1962-08-01), Wettstein et al.
Cocker et al., "Journ. of Med. Chemistry" (1965), pp. 417-425.
Atkinson et al., "Jour. of Med. Chemistry" (1965), Vol. 8, pp. 426-432.

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