Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2011-03-01
2011-03-01
Hartley, Michael G (Department: 1618)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S167000
Reexamination Certificate
active
07897586
ABSTRACT:
A stable anaesthetic composition is described which is particularly suitable for use in cats and dogs. The composition comprises an aqueous solution of an anaesthetically effective amount of a water soluble cyclodextrin or a cyclodextrin derivative complex of alfaxalone and a buffer, excluding phosphate buffer pH 7.0, 0.1M mixed as defined in the British Pharmacopoeia 1998, such that the pH of the solution is from 6.0-8.0.
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patent: 0 399 716 (1990-05-01), None
patent: 0 399 716 (1990-05-01), None
patent: 0 399 716 (1990-05-01), None
patent: PCT/AU93/00100 (1993-03-01), None
Development of a Non-Surfactant Formulation for Alfaxalone Through the Use of Chemically-Modified Cyclodextrins by Marcus E. Brewster, Kerry S. Estes, and Nicholas Bodor, Journal of Parenteral Science & Technology, pp. 262-265, 1989.
Parenteral Safety and Uses of 2-Hydroxypropyl B-Cyclodextrin, M.E. Brewster and N. Bodor, pp. 526-534, 1990.
Effect of 2-Hydroxypropyl-Cyclodextrin Complexes of the Neurosteroids, Alfaxalone, Pregnanolone and Pregnenolone, on Various Convulsant Stimuli in the Mousde, M.E. Brewster, W.R. Anderson, T. Loftsson, N. Bodor and E. Pop, pp. 511-514, 1996.
Anesthetic Activity and Pharmacokinetics of the Neurosteroid Alfaxalone Formulated in 2-Hydroxypropyl-Cyclodextrin in the Rat, M.E. Brewster, W.R. Anderson, A. Webb, N. Bodor and E. Pop, pp. 499-502, 1996.
A non-surfactant formulation for alfaxalone based on an amorphous cyclodextrin: Activity studies in rats and dogs, K.S. Estes, M.E. Brewster, A.I. Webb and N. Bodor, 1990, International Journal of Pharmaceutics, 65 (1990) 101-107.
Kieran Peter John
Lau Kai Kin
Patten Barry Edward
Hartley Michael G
Jurox Pty. Ltd.
SNR Denton US LLP
Westerberg Nissa M
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