An H-ANP peptide, pharmaceutical composition and method of use

Details An H-ANP peptide, pharmaceutical composition and method of use An H-ANP peptide, pharmaceutical composition and method of use

1984-12-21

1994-10-11

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530324, 530325, A61K 3702, C07K 710

Patent

active

053549007

ABSTRACT:
There are disclosed a new peptide .alpha.-hANP of the following structure: ##STR1## and acid addition salt thereof; a diuretic composition and a hypotensor composition containing the .alpha.-hANP or an acid addition salt thereof; and processes for the production thereof.

REFERENCES:
patent: 4496544 (1985-01-01), Needleman
patent: 4508712 (1985-04-01), Needleman
Life Sci. vol. 33, 297-302 (1983).
Biochem. & Biophys Res. Commun. 118, 131-139 (1984).
Science (1983) 71-73 vol. 221.
Biochem. & Biophys. Res. Commun. 122 (1984) 1076-1082.
Proc. of the Soc. Exper. Biol. Med. 170, 133-138 (1982).
Biochem. & Biophys. Res. Commun. (1983) 859-865 vol. 117, No. 3.
Can. Journal of Phys. & Pharm. 61, No. 2 (1983) 127-130.
Can. Journal of Phys. & Pharm. 60, No. 3, (1982) 324-330.
Life Sci. vol. 28, 89-94 (1980).
Jamieson, J. D. and Palade, G. E., "Specific Granules in Atrial Muscle Cells", The Journal of Cell Biology, vol. 23 (1964), pp. 151-172.
de Bold, A. J. et al, "A Rapid and Potent Natriuretic Response to Intravenous Injection of Atrial Myocardial Extract in Rats", Life Sciences, vol. 28 (1981), pp. 89-94.
Keeler, R., "Atrial Naturiuretic Factor has a Direct, Prostaglandin-independent Action on Kidneys", Can. J. Physiol. Pharmacol., vol. 60 (1982) pp. 1078-1082.
Currie, M. G. et al, "Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria", Science, vol. 221 (1983), pp. 71-73.

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