Amyloid specific binding peptides and detecting abeta peptide

Details Amyloid specific binding peptides and detecting abeta peptide Amyloid specific binding peptides and detecting abeta peptide

2004-04-07

2010-06-29

Saoud, Christine J (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

C530S350000, C530S391300, C435S007210, C435S007500, C435S008000, C424S009100, C424S009600

Reexamination Certificate

active

07745569

ABSTRACT:
Phage peptide display technology was used to identify peptides that bind specifically to the amyloid form of the Aβ1-40peptide. Peptides with similar structural features and bind to the amyloid form of Aβ1-40but not to monomeric Aβ1-40, are provided. Such peptides are useful as carrier molecules to deliver therapeutic and diagnostic reagents to amyloid plaques.

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