Amyloid precursor proteins and method of using same to assess ag

Details Amyloid precursor proteins and method of using same to assess ag Amyloid precursor proteins and method of using same to assess ag

1993-09-20

1997-08-12

Jacobson, Dian C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4352523, 43525411, 435348, 435358, 435365, 4353651, 435366, 536 235, 530839, C12N 115, C12N 121, C12N 510, C12N 1512

Patent

active

056564775

ABSTRACT:
This application describes a purified and isolated fragment of a nucleic acid molecule encoding an amyloid precursor mutein, wherein the fragment comprises a nucleic acid sequence encoding at least one marker and a nucleic acid sequence of about 419, about 475 or about 494 amino acid residues in which a portion thereof encodes a .beta.-amyloid protein domain. Also described is a method for screening for a compound which reduces the formation of .beta.-amyloid protein.

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