Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-05-29
1994-06-07
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 12, A61K 3702, A61K 3722
Patent
active
053189582
ABSTRACT:
A method is provided for potentiating the efflux of cholesterol from the macrophage, the method including the steps of increasing the affinity of high-density lipoprotein for macrophages by the administration of a serum amyloid A/high-density lipoprotein complex, exposing the macrophage to the complex, and potentiating macrophage cholesterol efflux.
REFERENCES:
Kisilevsky et al. Laboratory Investigation, vol. 66, No. 6, pp. 778-785, 1992.
Feussner et al. Electrophoresis, vol. 12 (4), pp. 283-286, 1991.
Cabana et al. J. Lipid Res., vol. 30, pp. 39-49, 1989.
Sipe et al. "Amyloid & Amyloidosis", International Symp. on Amyl., 1990, pp. 57-61.
Steinmetz et al. Bioch. Biophy. Acta, vol. 1006, pp. 173-178, (1989).
Glomset J. of Lipid Res., vol. 9, No. 2, pp. 155-167, 1968.
Koh Choon
Queen's University at Kingston
Wityshyn Michael G.
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