Amyloid binding assays

Details Amyloid binding assays Amyloid binding assays

2006-10-13

2010-06-29

Monshipouri, Maryam (Department: 1656)

Chemistry: analytical and immunological testing

Biological cellular material tested

Reexamination Certificate

active

07745222

ABSTRACT:
Provided herein are amyloid-binding assays that simulate in situ brain conditions by combining binders with various A-beta species on mammalian brain tissue. In general the amyloid-binding assays comprise the steps of (a) contacting a mammalian brain tissue sample with at least one A-beta species; (b) applying a putative binder to the brain tissue sample; and (c) determining whether the putative binder binds to the A-beta species.

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