Amylase inhibitor from wheat gluten using alcohol

Details Amylase inhibitor from wheat gluten using alcohol Amylase inhibitor from wheat gluten using alcohol

1974-01-23

1976-04-13

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07G 700

Patent

active

039503194

ABSTRACT:
An inhibitor for .alpha.-amylases, particularly pancreas amylase, is extracted from wheat, as for example, wheat flour or wheat gluten, by means of aqueous alcoholic solutions of lower alcohols of 1 to 3 carbon atoms, or dilute aqueous acid solutions having a pH of from 1 to 5, or of mixtures of the aqueous alcoholic solutions with dilute acids, and separating the desired amylase inhibitor contained in the aqueous phase from the extraction mixture by known methods. The amylase inhibitor thus obtained is particularly effective against pancreas amylase and is indicated as a therapeutic agent for the treatment of conditions resulting from alimentary hyperglycemia, such as adiposity, arteriosclerosis, diabetes and prediabetes.

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Arch - Biochemistry, Biochemistry, 9, pp. 235-249, (1946), Kneen et al.
Arch - Biochemistry, Biochemistry, 9, pp. 309-320 (1946), Militzer et al.

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