Amrinone-N-glucuronide, salts and cardiotonic use thereof

Details Amrinone-N-glucuronide, salts and cardiotonic use thereof Amrinone-N-glucuronide, salts and cardiotonic use thereof

1980-11-24

1982-06-15

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546256, 424180, 536 23, A61K 3144, C07D40514

Patent

active

043351310

ABSTRACT:
Amrinone-N-glucuronide or pharmaceutically-acceptable acid-addition or cationic salt thereof useful as cardiotonic agent is prepared by reacting amrinone with glucuronic acid or cationic salt thereof. Cardiotonic composition and method for increasing cardiac contractility using said amrinone-N-glucuronide or salt as active component are disclosed.

REFERENCES:
patent: 2384102 (1945-09-01), Lee et al.
patent: 4004012 (1977-01-01), Lesher
patent: 4072746 (1978-02-01), Opalka, Jr.
The Carbohydrates, Edited by Ward Pigman, pp. 406-419, Academic Press Inc., New York, 1957.

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