Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2000-12-07
2009-12-22
Yu, Melanie J. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007900, C435S007920, C435S283100, C435S287200, C435S288300, C435S288700
Reexamination Certificate
active
07635571
ABSTRACT:
Methods are disclosed for determining minute quantities of an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a substrate having an oxidant cleavable linker and a photosensitizer to come into close proximity. The photosensitizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay such as LOCI. The amount of product detected is related to the amount of analyte in the medium. Compositions, kits, and compounds are also disclosed.
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Davalian Dariush
De Keczer Steve
Singh Rajendra
Ullman Edwin F.
Leitereg Theodore J.
Siemens Healthcare Diagnostics Products GmbH
Yu Melanie J.
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