Amplification of nucleic acid sequences

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 5, 435 911, 435 912, 435 915, 435 94, 435183, 536 243, 536 2431, 536 2433, C12Q 168, C12Q 170, C12P 1934, C07H 2104

Patent

active

055938400

ABSTRACT:
A process for amplifying nucleic acid sequences from a DNA or RNA template which may be purified, or may exist in a mixture of nucleic acids. The resulting nucleic acid sequences may be exact copies of the template, or may be modified. The process has advantages over prior art amplification processes in that it increases the fidelity of copying a specific nucleic acid sequence, and it allows one to more efficiently detect a particular point mutation in a single assay.

REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 5427930 (1995-06-01), Birkenmeyer et al.

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