Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-01-04
1997-05-27
Walsh, Stephen
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530395, 435 691, C07K 14435, C12N 1512
Patent
active
056333480
ABSTRACT:
The present invention relates to an isolated nucleic acid fragment comprising a nucleic acid sequence coding for an amphotropic retrovirus receptor. This receptor is referred to as GLVR2 and has approximately 62% homology with the GLVR1 gene encoding for Gibbon Ape Leukemia Virus (GALV). Differences for the type of retroviruses interacting with the receptors exist. The protein encoding by the GLVR2 gene, cells transformed or transfected by the gene and vectors containing the gene are also disclosed.
REFERENCES:
patent: 5550221 (1996-08-01), Johann et al.
Sommerfelt, MA et al, Receptor Interference Groups of 20 Retroviruses Plating on Human Cells, Virology, vol. 176, No. 1, pp. 58-69, 1990.
Handelin, B. L., et al., Cell Surface Receptors for Murine Leukemia viruses: Two Assays and Their Implications, Virology, vol. 140, No. 1, pp. 183-187 (1985).
Kawakami, T.G., et al., Antigenic Studies on Gibbon Type-C Viruses, Transplantation Proceedings, Vo. VI, No. 2 (Jun.), pp. 193-196, 1974.
Kawakami, T.G., et al., Letters to Nature, Nature New Biology, vol. 235, pp. 170-171, (1972).
Kawakami, T.G., et al., Onocogenicity of Gibbon Type-C Myelogenous Leukemia Virus, Int. J. Cancer: 25, 641-646 (1980).
Sanger, F., et al., DNA sequencing with chain-terminating inhibitors, Proc. Natl. Acad Sco, USA, vol. 74, No. 12, pp. 5463-5467, 1977.
O'Hara, B., et al., Characterization of a Human Gene Conferring Sensitivity to Infection by Gibbon Ape Leukemia Virus, Cell Growth & Differentiation, vol. 1: 119-127, 1990.
Kaelbling, M. et al., Localization of the Human Gene Allowing Infection by Gibbon Ape Leukemia Virus to Human Chromosome Region 2q11-q14 and to the Homologous Region on Mouse Chromosome 2, Journal of Virology, vol. 65, No. 4, pp. 1743-1747 (1991).
Garcia, J. V., eta l., Localization of the Amphotropic Murine Leukemia Virus Receptor Gene to the Pericentromeric Region of Human Chromosome 8, Journal of Virology, vol. 65, No. 11, pp. 6316-6319, 1991.
Macleod et al., Mol. Cell. Biol. vol. 10, p. 3663, 1990.
Johann Stephen V.
O'Hara Bryan M.
van Zeijl Marja
American Cyanamid Company
Barnhard Elizabeth M.
Lowney Karen A.
Teng Sally P.
Walsh Stephen
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