Amphotericin complexes containing citric acid and calcium

Details Amphotericin complexes containing citric acid and calcium Amphotericin complexes containing citric acid and calcium

1976-03-08

1977-10-18

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, C07H 1708

Patent

active

040547345

ABSTRACT:
This invention relates to new forms of amphotericin B which comprise amphotericin B, an acid anion, and calcium ion. These new forms of amphotericin retain the activity of amphotericin and have the particular advantage of being soluble in acidic or alkaline solutions.

REFERENCES:
patent: 2631143 (1953-03-01), Braker et al.
patent: 3244590 (1966-04-01), Schaffner et al.
patent: 3928570 (1975-12-01), Metzger
patent: 3957754 (1976-05-01), Aszalos et al.
patent: 3965090 (1976-06-01), Metzger
Hooper et al., "Chem. Abst.," vol. 55, 1961, p. 2025(c).

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