Amphotericin B methyl ester salts

Details Amphotericin B methyl ester salts Amphotericin B methyl ester salts

1976-02-23

1977-08-09

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, 536 18, 536115, C07H 1708

Patent

active

040412326

ABSTRACT:
Amphotericin B methyl ester salts, such as salts formed by reaction with mono and dicarboxylic amino acids (such as aspartic acid, or glutamic acid or pyroglutamic acid), hydroxy carboxylic acids (such as lactic acid) and mono and dicarboxylic acids (such as acetic acid) are provided and have been found to be readily water-soluble and at least as stable and active as the parent ester compound.

REFERENCES:
patent: 3945993 (1976-03-01), Schaffner et al.

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