Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-10
1994-08-02
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 89, C07D491052, A61K 31445
Patent
active
053345940
ABSTRACT:
Novel amphoteric tricyclic compound represented by the following formula: ##STR1## wherein R.sup.1 represents a hydrogen atom or a halogen atom; X represents --O--, --CH.sub.2 O--, or --OCH.sub.2 --; and Y represents a C.sub.2 -C.sub.5 alkylene group which may optionally be substituted with a lower alkyl group, and a pharmacologically acceptable salt thereof are disclosed. Also disclosed are a pharmaceutical composition comprising the same and a method for treatment of an allergic disease or bronchial asthma.
REFERENCES:
The Merck Index, 11th edition, Azatadine, 917, p. 144, (1989).
The Merck Index, 11th edition, Loratadine, 5455, p. 877 (1989).
Ito Yasuo
Iwasaki Nobuhiko
Kado Noriyuki
Kato Hideo
Nishino Hiroyuki
Cintins Marianne M.
Hokoriku Pharmaceutical Co., Ltd.
Spivack Phyllis G.
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