Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2002-02-21
2008-08-05
Badio, Barbara P (Department: 1612)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C540S107000, C540S108000, C540S113000, C435S320100, C424S450000
Reexamination Certificate
active
07407947
ABSTRACT:
An amphoteric compound based on a sterol skeleton, the 3-position of the sterol ring system being substituted by one or more amphoteric groups having an isoelectric point of between about 4 and 9, together with liposomes containing such compounds and their uses.
REFERENCES:
patent: 4788182 (1988-11-01), Baschang et al.
patent: 4891208 (1990-01-01), Janoff et al.
patent: 5888821 (1999-03-01), Reszka
patent: 5993823 (1999-11-01), Gras-Masse et al.
patent: 0169812 (1986-01-01), None
patent: 02331417 (1990-11-01), None
patent: WO 93/05162 (1993-03-01), None
patent: WO 96/11023 (1996-04-01), None
patent: WO 96/20208 (1996-07-01), None
patent: WO 97/45442 (1997-12-01), None
patent: WO 00/43994 (1998-10-01), None
patent: WO 00/09073 (2000-02-01), None
patent: WO 00/28972 (2000-05-01), None
patent: WO 00/30688 (2000-06-01), None
patent: WO 00/59474 (2000-10-01), None
patent: WO 01/64330 (2001-09-01), None
Rieko Tachibana et al.,Intracellular Regulation of Macromolecules Using pH-Sensitive Liposomes&Nuclear Localization Signal: Qualitative&Quantitative Evaluation of Intracellular Trafficking, pp. 538-544, 1998.
S. BandHandbook of Chemistry and Physics, 73, 8-37 FF, date needed.
C. Nastruzzi et al.,Liposomes as Carriers for DNA-PNA Hybrids, Aug. 10, 2000, pp. 237-249.
Toyoaki Ishikura et al.,Preparation of Peptide-Lipid Derivatives and Liposomes Containing the Derivatives, Aug. 9, 1994.
Ehud M. Landau,Transfer of Structural Information from Langmuir Monolayers to Three-Dimensional Growing Crystals, 1985.
A. Pieurdeau et al.,Synthesis of Polymers with Pharmacological Properties. Introduction of Peptide Sequences into the Macromolecular Chain, 1981.
V. Budker et al.,pH-Sensitive, Cationic Liposomes: A New Synthetic Virus-Like Vector, Jun. 1996, pp. 760-764.
Ismall M. Hafez et al.,Tunable pH-Sensitive Liposomes Composed of Mixtures of Cationic and Anionic Lipids, 2000.
Xiao-Jun Li et al.,Theory of Tunable pH Sensitive Vesicles of Anionic and Cationic Lipids or Anionic and Neutral Lipids, Sep. 22, 2000.
G. Hermanson,Bioconjugate Techniques.
Fuxing Tang et al “Introduction of a Disulfide Bond into a Cationic Lipid Enhances Transgene Expression of Plasmid DNA” Department of Pharmaceutics, University of Florida. Received Nov. 26,1997,Biochemical and Biophysical Research Communications 242, 141-145 (1998).
Thomas Fichert et al. “Synthesis and Transfection Properties of Novel Non-Toxic Monocationic Lipids. Variation of Lipid Anchor, Spacer and Head Group Structure.” Tumor Biology Center, Department of Clinical Research, Germany. Received Oct. 4, 1999; accepted Feb. 8, 2000, Bioorganic & Medicinal Chemistry Letters 10 (200) 787-791.
El-Mokdad Nasr
Endert Gerold
Fankhaenel Stefan
Panzner Steffen
Akerman & Senterfitt
Badio Barbara P
Lefkowitz Gregory M.
Nelson Gregory A.
Novosom AG
LandOfFree
Amphoteric sterols and the use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amphoteric sterols and the use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amphoteric sterols and the use thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4015786