Amphiphilic trisulfonated porphyrazines for photodynamic...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C540S132000, C436S548000

Reexamination Certificate

active

07541457

ABSTRACT:
Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-soluble amphiphilic porphyrazines are substituted with different alkylyl, aryl, aminoalkyl and aminoaryl groups, with or without carboxyl moeity.

REFERENCES:
patent: 5756541 (1998-05-01), Strong et al.
patent: 5864044 (1999-01-01), Van Lier et al.
patent: WO-01/42368 (2001-06-01), None
Tian et al. “Synthesis of water soluble trisulfonated phthalocyanines via palladium-catalysed cross coupling reactions” Tetrahedron Letters, 2000, vol. 41, pp. 8435-8438.
Margaron, P et al., Photochemistry and Photobiology, vol. 63, No. 2, 1996, pp. 217-223.
Oleinick, N.L., et al., Photochem. Photobiol. Sci., vol. 1, 2002, pp. 1-21.
Quam, T. et al., Investigative Ophthalmology & Visual Science, vol. 42, No. 10, Sep. 2001, pp. 2408-2413.
Sharman, W.M. et al., DDT, vol. 4, No. 11, Nov. 1999, pp. 507-517.
Tian, H. et al., Tetrahedron Letters, vol. 41, 2000, pp. 8435-8438.
Li, Z et al., Canadian Journal of Chemistry, vol. 77, No. 1, 1999, pp. 138-145.
Database Beilstein, Beilstein Institute for Organic Chemistry, Frankfurt-Main, De; Citation No. 6187722, XP002295842, Beilstein Registry No. 8333585 and Beilstein Reaction ID 5201875.
Ottoni, O et al., Tetrahedron, Elsevier Science Publishers, Amsterdam, NL, vol. 54, No. 46, Nov. 12, 1998, pp. 13915-13928.
Artico, M et al., Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 39, No. 2, Jan. 19, 1996, pp. 522-530.
Kudrevich, S et al., Journal of Medicinal Chemistry, Nov. 21, 1997, vol. 40, No. 24, pp. 3897-3904.
Kliesh, H. et al., Liebigs Annalen: Organic and Bioorganic Chemistry, VCH Publishers, US, No. 10, Oct. 1995, pp. 1269-1274.
Aoudia, M. et al., Journal of the American Chemical Society, American Chemical Society, Washington, DC, US, vol. 119, No. 26, 1997, pp. 6029-6039.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Amphiphilic trisulfonated porphyrazines for photodynamic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amphiphilic trisulfonated porphyrazines for photodynamic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amphiphilic trisulfonated porphyrazines for photodynamic... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4096713

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.