Amphiphilic polymer capsules and related methods of...

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – At least one aryl ring which is part of a fused or bridged...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C524S800000, C524S801000, C524S802000, C524S804000, C524S812000, C524S819000, C524S821000, C524S822000, C524S823000, C524S824000, C524S832000, C524S833000, C524S845000, C524S846000, C424S451000

Reexamination Certificate

active

07989544

ABSTRACT:
Polymer capsules from amphiphilic graft copolymers comprising reactive, hydrophobic polyolefin backbones, and hydrophilic poly(ethylene glycol) (PEG) grafts are produced by self-assembly of the polymers at the oil-water interface, and crosslinking the assembly with bis-cyclooctene PEG derivatives in conjunction with ring-open metathesis polymerization catalysts. The use of the graft copolymer architecture in capsule synthesis provides significant opportunities to tune both the surface properties, in terms of recognition, and the membrane properties, in terms of mechanical strength, encapsulation, and release.

REFERENCES:
patent: 4931362 (1990-06-01), Zsifkovits et al.
patent: RE35717 (1998-01-01), Nahm
patent: 6479592 (2002-11-01), Rheinberger et al.
patent: 6558665 (2003-05-01), Cohen et al.
patent: 6835394 (2004-12-01), Discher et al.
patent: 7160969 (2007-01-01), Piccinelli et al.
patent: 2003/0087985 (2003-05-01), Hubbell et al.
patent: 2003/0125237 (2003-07-01), Kim et al.
patent: 2003/0203991 (2003-10-01), Schottman et al.
patent: 2004/0032038 (2004-02-01), Ali et al.
patent: 2004/0138329 (2004-07-01), Hubbell et al.
patent: 2004/0185107 (2004-09-01), Rubinstein et al.
patent: 2004/0197357 (2004-10-01), Heming et al.
patent: 2004/0208930 (2004-10-01), Yoneda et al.
patent: 2004/0219216 (2004-11-01), Rubinstein et al.
patent: 2004/0228831 (2004-11-01), Belinka et al.
patent: 2004/0234590 (2004-11-01), Mane et al.
patent: 2004/0247675 (2004-12-01), Gruber
patent: 2004/0253184 (2004-12-01), Li et al.
patent: 2004/0266944 (2004-12-01), Wiercinski et al.
patent: 2004/0267354 (2004-12-01), Ringeisen et al.
patent: 2005/0008690 (2005-01-01), Miller
patent: 2005/0019371 (2005-01-01), Anderson et al.
patent: 2005/0019399 (2005-01-01), Fischer et al.
patent: 2005/0019409 (2005-01-01), Edgren et al.
patent: 2006/0058476 (2006-03-01), Piccinelli et al.
Kurt Breitenkamp, E.A. Novel Polymer Capsules from Amphiphilic Graft Copolymers and Cross-Metathesis. J. Am. Chem. Soc., vol. 125, No. 40, Dec. 9, 2003, pp. 12070-12071, XP002503995.
Mir Mukkaram Ali, E.A. Polymeric Capsules Prepared in Situ Synthesis and Cross-Linking of Amphiphilic Copolymer by Atom Transfer Radical Polymerization. Macromolecules, vol. 36, No. 6, Jan. 3, 2003 pp. 1793-1801 XP002503996.
Ruxandra Gref, E.A. Biodegradable Long-Circulating Polymeric Nanospheres. Science, vol. 263, No. 5153, Mar. 18, 1994 pp. 1600-1603, XP002503997.
Vladimir P. Torchilin. Structure and design of polymeric surfactant-based drug delivery systems. Journal of Controlled Release, vol. 73, No. 2-3, Jun. 15, 2001, pp. 137-172, XP004246457 *p. 144-153*.
Helmut Ringsdorf, E.A. Molekulare Architektur und Funktion von polymeren orientierten Systemen—Modelle fur das Studium von Organisation, Oberflachenerkennung und Dynamik bei Biomembranen. Angew. Chem., vol. 100, No. 1, Jan. 1988, pp. 117-162, XP002503999.
Kurt Breitenkamp, E.A. Novel Amphiphilic Graft Copolymers Prepared by Ring-Opening Metathesis Polymerization of Poly(ethylene glycol)-Substituted Cycootene Macromonomers. Macromolecules, vol. 35 No. 25, Nov. 6, 2002, pp. 9249-9252, XP002504000.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Amphiphilic polymer capsules and related methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amphiphilic polymer capsules and related methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amphiphilic polymer capsules and related methods of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2769955

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.