Amphiphilic compounds derived from amino acids or peptides, thei

Details Amphiphilic compounds derived from amino acids or peptides, thei Amphiphilic compounds derived from amino acids or peptides, thei

1995-06-07

1997-07-22

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, 514 25, 530324, 530327, 530328, 530329, 530330, 530331, 530332, 536 41, A61K 3805, A61K 3800, C07G 300

Patent

active

056503938

ABSTRACT:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.

REFERENCES:
patent: 5446023 (1995-08-01), Pavia et al.
Ferrari et al., "Artificail Carbohydrate Antigen: The Synthesis of Glycopeptidic Haptens with T(N) Specificity", Bioorganic Chemistry, vol. 11, pp. 85-95. 1982.

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