Amphiphilic compounds derived from amino acids or peptides, thei

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, A61K 3800, A61K 3802

Patent

active

056375646

ABSTRACT:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.

REFERENCES:
patent: 2785152 (1957-03-01), Jonas
patent: 2830983 (1958-04-01), Lemieux
patent: 5446023 (1995-08-01), Pavia et al.
Ferrari, B., et al. Artificial carbohydrate antigens: the synthesis of glycopeptidic haptens with T.sub.N specificity. Bio. Org. Chem. 11(1):85-95 (1982).
Kiwada, et al. Application of synthetic liposomes based on acyl amino acids or acyl peptides as drug carriers. Chem. Pharm. Bull., 35:2935-1942 (1987).
Larrabee, C.E., et al. Radiation-induced polymerization of sodium 10-undecenoate in aqueous micelle solutions. J. Polymer Sci. Polyn. Lett. Ed. 17:749-751 (1979).
LeBlanc, M. et al. Use of lymphoblastoid Namalva cell cultures in a toxicity test. Application to the monitoring of detoxification procedures for fluorocarbons to be used as intravascular oxygen-carriers. Pharm. Res. 246 (1985).
Liposome Technology. Targeted Drug Delivery and Biological Interaction. vol. III. (G. Gregoriadis ed., CRC Press, Inc., (1984).
Ogawa, T., et al. Enhancement of serum antibody production in mice by oral administration of lipophilic derivatives of muramylpeptides and bacterial lipopolysaccharides with bovine serum albumin. Chem. Abstracts 105:305q (1986).
Okahata, Y., et al., Functional capsule membranes. Part 29. Concanavalin A-induced permeability control of capsule membranes corked with synthetic glycolipid bilayers or grafted with synthetic glycopolymers. J. Chem. Soc. Perkin Trans. II p. 1317 (1987).
Ozer, et al., A novel drug delivery system: non-ionic surfactant vesicles. European Journal of Pharmaceutical and Biopharmaceutics. 37:75-79 (1991).
Okahata, Y., et al., Functional capsule membranes. Part 28..sup.1 A capsule membrane grafted with viologen-containing polymers as a reactor of electron-transfer catalysis in heterophases. J. Chem. Soc. Perkin Trans. II p. 1003 (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Amphiphilic compounds derived from amino acids or peptides, thei does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amphiphilic compounds derived from amino acids or peptides, thei, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amphiphilic compounds derived from amino acids or peptides, thei will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-764600

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.