Amphiphilic compounds containing two sugar or sugar-derived head

Details Amphiphilic compounds containing two sugar or sugar-derived head Amphiphilic compounds containing two sugar or sugar-derived head

1994-06-07

1995-04-04

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, 536 176, 536 221, 536 54, 536122, 536124, C07H 1502, A61K 9133, B01F 1756

Patent

active

054039223

ABSTRACT:
The subject of the invention is a surface-active composition, comprising a bolaamphiphile or bolaform chemical compound, containing a linear or branched, hydrophobic carbon chain at the two ends of which are arranged two hydrophilic portions or head group groups, corresponding to the following general formula:

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Menger and Wrenn, 1976, J. Phys. Chem 80: (24) 2651 "Interfacial and Micellar Properties of Bolaform Electrolytes".
Fuhrhop et al., 1986, J. Am. Chem. Soc. 108: 1785 "Bloaamphiphiles and Monolayer Lipid Membranes Made From 1,6,19,24-Tetraoxa-3,21-cyclohexatriacontadiene-2,5,20,23-tetrone".
Tschierske and Zaschke, 1990, J. Chem. Soc. Chem. Commun. p. 1013 "Novel Thermotropic and Lyotropic Double Headed Diol-based Mesogens".
Emmerling et al, 1981, Starch [Iacuna] 33: (6) 202-208 "Preparative Methods for the Preparation of Higher Maltooligomers and their Coupling with Aliphatic Diamines".
Furhop et al., 1984, Angewandte Chemie 23: 100-113 "Routes to Functional Vesicle Membranes Without Proteins".
Hjelmeland, et al., Analytical Biochem., 1983 130: 485-490. "A New Class of Nonionic Detergents with a Gluconamide Polar Group".

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