Amphipathic, micellar delivery systems for biologically active p

Details Amphipathic, micellar delivery systems for biologically active p Amphipathic, micellar delivery systems for biologically active p

1994-12-29

1997-06-03

Stone, Jacqueline M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424490, 424498, 424502, 935 54, 5483415, 514400, A61K 4800, A61K 3166, A61K 31415

Patent

active

056354878

ABSTRACT:
The present invention provides a composition comprising a population of micelles wherein each micelle comprises at least one amphipathic compound layer that surrounds a non-aqueous core that contains a polyion. Also provided are a method of preparing such a composition and the uses of such compositions for delivering biologically active polyions to cells.

REFERENCES:
patent: 5151264 (1992-09-01), Samain et al.
Behr J.P., Demeneix B., Loeffler J.P., Perez-Mutul J. Efficient Gene Transfer into Mammalian . . . P.N.A.S. 86:6982-6986 Sep. 1989.

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