Amphipathic compound and liposome comprising the same

Details Amphipathic compound and liposome comprising the same Amphipathic compound and liposome comprising the same

1992-08-11

1993-04-27

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424417, 530323, 530330, 530331, 554106, 554110, 560169, 560170, 560171, A61K 9127, A61K 3702, C07C22900

Patent

active

052060276

ABSTRACT:
An amphipathic compound, which includes a succinic acid moiety and an amino acid moiety and is designed so as to form a stable unilayer liposome, and a negatively charged liposome comprising said amphipathic compound as a membrane-component are disclosed. The amphipathic compound of the present invention gives liposomes which minimize the leakage of a drug encapsulated therein and scarcely undergo association, aggregation or precipitation.

REFERENCES:
patent: 5116992 (1992-05-01), Braquet
CA 112:115032 (1990).
Leventis et al., Biochemistry 26 3267-3276 (1987).

Affiliated with

Also associated with

Rating

Amphipathic compound and liposome comprising the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amphipathic compound and liposome comprising the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amphipathic compound and liposome comprising the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2325511