Amphetamine protein complex as immunogen for obtaining antibodie

Details Amphetamine protein complex as immunogen for obtaining antibodie Amphetamine protein complex as immunogen for obtaining antibodie

1991-02-07

1993-08-03

Lacey, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303871, 5303881, 530405, 435 7021, 4351722, 43524027, 424 88, C07K 1528, C12N 512

Patent

active

052330257

ABSTRACT:
A N-(4-aminobutyl)amphetamine-protein complex has been synthesized to be used as an immunogen to prepare an antibody having a higher affinity to methamphetamine that to the hapten N-(4-aminobutyl)amphetamine. The antibody prepared by the use of the complex has 1,000 times the affinity to methamphetamine as that of an antibody prepeared by the use of N-(4-aminobutyl)methamphetamine-protein complex as an immunogen.

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