Amorphous rapamycin 42-ester with...

Details Amorphous rapamycin 42-ester with... Amorphous rapamycin 42-ester with...

2007-08-10

2008-11-04

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C540S456000

Reexamination Certificate

active

07446111

ABSTRACT:
The present invention provides an amorphous form of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid. This invention also provides processes for preparing the amorphous form and pharmaceutical compositions including the amorphous form.

REFERENCES:
patent: 5362718 (1994-11-01), Skotnicki et al.
patent: 5989591 (1999-11-01), Nagi
patent: 6004973 (1999-12-01), Guitard et al.
patent: 6197781 (2001-03-01), Guitard et al.
patent: 6599535 (2003-07-01), Guitard et al.
patent: 7271177 (2007-09-01), Benjamin
patent: 2004/0077677 (2004-04-01), Ashraf et al.
patent: 2005/0152983 (2005-07-01), Ashraf et al.
patent: WO 01/23395 (2001-04-01), None
patent: WO 2004/026280 (2004-04-01), None
patent: WO 2005/070393 (2005-08-01), None
Lee et al, Particle Size Reduction in “Water Insoluble Drug Formulations”, (R. Liu, Ed.) Interpharm Press Co., Denver, CO 392-473, (2000).
Vippagunta et al, “Crystallline Solids”, Adv. Drug Del. Rev., 48(1):3-26, (May 16, 2001).
Farmacia Hospitalaria, pp. 1590-1592, 2004.
Monographs on Chemical Derivatives, Stearic Acid, 2004.
Atkins, P., Physical Chemistry, 2ndEdition, 1996.

Affiliated with

Also associated with

Rating

Amorphous rapamycin 42-ester with... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amorphous rapamycin 42-ester with..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amorphous rapamycin 42-ester with... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4038798