Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-09-09
1997-09-30
Owens, Amelia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546197, A61K 3144
Patent
active
056726120
ABSTRACT:
A free-flowing, amorphous paroxetine hydrochloride-ethanol composition suitable as a therapeutic agent for premature ejaculation can be prepared by dissolving paroxetine free base in a hydrochloric acid-ethanol solution followed by drying. In a preferred embodiment, the amount of ethanol present in the amorphous product is in the range of 1 to 4 weight percent based on paroxetine hydrochloride. The amorphous product is stable and substantially non-hygroscopic.
REFERENCES:
patent: 4007196 (1977-02-01), Chistensen et al.
patent: 4721723 (1988-01-01), Barnes et al.
patent: 5151448 (1992-09-01), Crenshaw et al.
patent: 5276042 (1994-01-01), Crenshaw et al.
El-Rashidy Ragab
Ronsen Bruce
Owens Amelia
Pentech Pharmaceuticals, Inc.
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