Amorphous form of a phosphoric acid salt of a dipeptidyl...

Details Amorphous form of a phosphoric acid salt of a dipeptidyl... Amorphous form of a phosphoric acid salt of a dipeptidyl...

2005-09-09

2009-11-03

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S350000

Reexamination Certificate

active

07612072

ABSTRACT:
The present invention relates to a novel amorphous form of the dihydrogenphosphate salt of (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-α]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine of structural formula I as well as a process for its preparation, pharmaceutical compositions containing this novel form, and methods of use of the novel form and pharmaceutical compositions for the treatment of diabetes, obesity, and high blood pressure.

REFERENCES:
patent: 6699871 (2004-03-01), Edmondson et al.
patent: 2003/0100563 (2003-05-01), Edmondson et al.
patent: 2005/0032804 (2005-02-01), Cypes et al.
patent: 2006/0287528 (2006-12-01), Wenslow et al.
patent: 2007/0021430 (2007-01-01), Chen et al.
patent: WO 03/004498 (2003-01-01), None
patent: WO 2005/003135 (2005-01-01), None
patent: WO 2005/020920 (2005-03-01), None
patent: WO 2005/020920 (2005-03-01), None
patent: WO 2005/030127 (2005-04-01), None
patent: WO 2005/072530 (2005-08-01), None

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