Amorphous drug beads

Details Amorphous drug beads Amorphous drug beads

2007-01-16

2007-01-16

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S489000, C424S490000, C424S492000, C424S496000, C424S498000

Reexamination Certificate

active

10207975

ABSTRACT:
The present inventive subject matter relates to amorphous drug beads comprising an amorphous active drug and an organic surfactant having improved solubility, absorption and wettability characteristics. The present inventive subject matter further relates to methods of preparing the amorphous drug beads, wherein molten drug beads are subject to a cooling step with or without shear.

REFERENCES:
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 5118528 (1992-06-01), Fessi et al.
patent: 5246707 (1993-09-01), Haynes
patent: 5858410 (1999-01-01), Muller et al.
patent: 6395300 (2002-05-01), Straub et al.
patent: WO 9744014 (1997-11-01), None
patent: WO 98/57967 (1998-12-01), None
patent: WO 9857967 (1998-12-01), None

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