Ammonium fluorometallate containing compositions

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424131, 424140, 424144, 424145, 424147, 424151, A61K 718, A61K 722, A61K 3316, A61K 3330

Patent

active

044303246

ABSTRACT:
The present invention discloses a composition, comprising: (i) an amount of ammonium fluorometallate effective to treat, control or substantially prevent oral problems, diseases or conditions; and (ii) a carrier for said fluorometallate suitable for use in the oral cavity. It also discloses a method for treating, controlling or substantially preventing oral problems, diseases or conditions which consists essentially of contacting dental tissues, surfaces or oral cavity with ammonium fluorometallate or a preparation thereof including nonfluoro ammonium metallate.

REFERENCES:
patent: 3201316 (1965-08-01), Norris
patent: 3490866 (1970-01-01), Muhler
patent: 3937804 (1976-02-01), Delaney et al.
Caries Research 3:315-325, "A Clinical Trial On the Caries-Inhibiting Effect of Sodium Hexafluorostannate" (Moller et al.).
Caries Research 4:269-282, "The Caries Inhibiting Effect of Topically Applied Hexafluorostannate on Dentine and Enamel" (von der Fehr).
Arch. Oral Biol. 1974, 947-950, "Incorporation of Fluoride In Bones and Teeth and Dental Fluorosis in Mice After Administration of Complex Fluorides" (Ruzicka et al.).
J. Am. Dent. Assoc. 1978, 96, 459-463, "Dental Fluorosis as Related to the Concentration of Fluoride in Teeth and Bone" (Brudevold et al.).

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