Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-12-15
2008-10-28
Andres, Janet L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S321000
Reexamination Certificate
active
07442714
ABSTRACT:
The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.
REFERENCES:
patent: 0 089 167 (1986-10-01), None
patent: 0089167 (1986-10-01), None
patent: 0 244 944 (1990-01-01), None
patent: 19950007228 (1995-07-01), None
patent: 2004100696 (2004-12-01), None
patent: WO 02/079158 (2002-10-01), None
patent: WO 03/089414 (2003-10-01), None
See Hcaplus 136:334518.
Choi Jin Young
Jang Jeong-soo
Jang Woo Jae
Kim Jae-Sun
Kum Do Seung
Andres Janet L.
Frommer & Lawrence & Haug LLP
Robinson Binta
Santucci Ronald R.
SK Chemicals Co. Ltd.
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