Amitriptyline conjugates to antigenic proteins and enzymes

Details Amitriptyline conjugates to antigenic proteins and enzymes Amitriptyline conjugates to antigenic proteins and enzymes

1980-04-07

1981-12-22

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 37, 564380, 2603264, 424 12, C07C 87459, C07C10128, C07C10134

Patent

active

043072453

ABSTRACT:
Amitriptyline functionalized compounds are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays for the determination of amitriptyline, while the enzyme conjugate finds use in a homogeneous enzyme immunoassay for the determination of amitriptyline.

REFERENCES:
patent: 3234279 (1966-02-01), Kollonitsch et al.
patent: 3309404 (1967-03-01), Engelhardt
patent: 3324170 (1967-06-01), Kollonitsch
patent: 3372196 (1968-03-01), Engelhardt
patent: 3379750 (1968-04-01), Kollonitsch
patent: 3445519 (1969-05-01), Kollonitsch
patent: 3818020 (1974-06-01), Huebner
patent: 3981917 (1976-09-01), Engelhardt

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