Amitriptyline conjugates to antigenic proteins and enzymes

Details Amitriptyline conjugates to antigenic proteins and enzymes Amitriptyline conjugates to antigenic proteins and enzymes

1978-12-29

1980-09-16

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 2601125R, 424177, 424 88, A61K 3900, A61K 4502

Patent

active

042230136

ABSTRACT:
Amitriptyline functionalized compounds are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays for the determination of amitriptyline, while the enzyme conjugate finds use in a homogeneous enzyme immunoassay for the determination of amitriptyline.

REFERENCES:
patent: 3852157 (1974-12-01), Rubenstein
patent: 4069105 (1978-01-01), Singh
Chemical Abstracts, vol. 77 (1972), p. 43092p.
Chemical Abstracts, vol. 84 (1976), p. 159527h.

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