Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-01-25
2009-08-04
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S129000, C546S132000
Reexamination Certificate
active
07569582
ABSTRACT:
The present invention relates to compounds of formula (I) as defined herein that are melanocortin receptor agonists, to the preparation thereof and to the therapeutic use thereof in the treatment and in the prevention of obesity, diabetes and sexual dysfunctions that can affect both sexes, in the treatment of cardiovascular diseases, and also in anti-inflammatory uses or in the treatment of alcohol dependency.
REFERENCES:
patent: 5968929 (1999-10-01), Blythin et al.
patent: WO 02/059095 (2002-08-01), None
patent: WO 03/061660 (2003-07-01), None
Haqq et al., The Journal of clinical endocrinology and metabolism, (Jan. 2003) vol. 88, No. 1, pp. 174-178.
Holder, J.R., et. al., Melanocortin Ligands: 30 Years of Structure-Activity Relationship (SAR) Studies, Medicinal Research Reviews vol. 24, No. 3, pp. 325-356 (2004).
Irani, B.G., et. al., Progress in the Development of Melanocorting Receptor Selective Ligands, Current Pharmaceutical Design vol. 10, No. 28 (2004) pp. 3443-3479 (37).
Braun Alain
Cornet Bruno
Courtemanche Gilles
Crespin Olivier
Pascal Cecile
Gupta Balaram
Rahmani Niloofar
Sanofi-Aventis
Seaman D. Margaret
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