Aminothiol compound

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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06861536

ABSTRACT:
The present invention discloses an aminothiol compound having a general formula I wherein R1-R5are substitutable ligands. Such compounds can perform as superior catalysts in asymmetric addition reactions of organic zinc and aldehyde. According to the present invention, the compounds is needed only less than 0.02% of main reactants to obtain enantioselectivity higher than 99% enantiomeric excess, whereby the asymmetric reactions can become very economic.

REFERENCES:
Hsu, et al, 2001, J. Org. Chem, 66, 8573-8584.*
Kossenjams, et al, 1999, J. Chem. Soc., Perkin Trans., 1, 2353-2365.*
Kang et al, 1997, CAS:126:131036.*
Kang et al, 1995, CAS:122:55341.*
Carreno et al., 1990, CAS:113:131411.

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