Aminothiazoles

Details Aminothiazoles Aminothiazoles

1979-11-16

1981-12-22

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548190, 548193, C07D27738

Patent

active

043071066

ABSTRACT:
A series of 2-aralkylaminothiazoles and the pharmaceutically acceptable acid addition salts thereof having anti-inflammatory and immune regulant activity are disclosed. Preferred compounds include 2-phenethylamino-4-phenyl-thiazole, 2-(p-methoxyphenethylamino)-4-(p-fluorophenyl)-thiazole, 2-phenethylamino-4-phenyl-5-methyl-thiazole, 2-thenylamino-4-phenyl-thiazole and 2-thenylamino-4-(p-fluorophenyl)-thiazole.

REFERENCES:
patent: 3299087 (1967-01-01), Spivack et al.
patent: 3458526 (1969-07-01), Lednicer
Kaye et al., JACS 74, 2271 (1952).
Bhattacharya, Jour. Ind. Chem. Soc. 44, 57 (1967).
Biniecki et al., Acta Polon. Pharm. 19, 103 (1962).
CA 59, 1613e (1963).

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