Aminothiazole substituted penicillins and antibacterial composit

Details Aminothiazole substituted penicillins and antibacterial composit Aminothiazole substituted penicillins and antibacterial composit

1986-07-25

1989-03-28

Lone, Werren B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540316, 540328, A61K 3143, C01D19954

Patent

active

048164526

ABSTRACT:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: ##STR1## wherein R.sup.1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C.sub.2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.

REFERENCES:
patent: 3936443 (1976-02-01), Gregson et al.
patent: 4284631 (1981-08-01), Takaya et al.
patent: 4344939 (1972-08-01), Niemers et al.
patent: 4376203 (1983-03-01), Heyles et al.
patent: 4507487 (1985-03-01), Kamachi et al.
Chem. Abs. (1977), 87, p. 480, 53335r.

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