Aminotetralin derivative and compositions and method of use ther

Details Aminotetralin derivative and compositions and method of use ther Aminotetralin derivative and compositions and method of use ther

1997-02-21

1998-09-15

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

564428, A61K 31135, C07C21774

Patent

active

058078975

ABSTRACT:
The invention relates to aminotetralin derivatives of the formula I: ##STR1## wherein: R.sup.1 is methyl or ethyl; R.sup.2 is hydrogen, halogen, lower-alkoxy or thiolower-alkyl; R.sup.3 is hydrogen, halogen, lower-alkoxy or lower-alkyl; and the chiral center * is in the (S)(-) form; or a pharmaceutically acceptable acid-addition salt thereof, with the proviso that when R.sup.2 and R.sup.3 are both hydrogen, R.sup.1 must be methyl; to pharmaceutical compositions containing them and to methods for the treatment or prevention of movement disorders utilizing them.

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