Aminosulfonyl urea ACAT inhibitors and a method of lowering bloo

Details Aminosulfonyl urea ACAT inhibitors and a method of lowering bloo Aminosulfonyl urea ACAT inhibitors and a method of lowering bloo

1993-02-19

1994-02-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 31175

Patent

active

052887570

ABSTRACT:
The present invention provides pharmaceutically useful compounds which are aminosulfonyl urea compounds which are ACAT inhibitors rendering them useful in controlling blood cholesterol levels, pharmaceutical compositions and methods of using the ACAT inhibitors and closely related compounds which are also aminosulfonyl urea compounds.

REFERENCES:
patent: 2312404 (1943-03-01), Haack
patent: 3242174 (1966-03-01), McManus et al.
patent: 4515620 (1985-05-01), Bohner
J. Med. Chem., vol. 8, McManus, et al., pp. 766-776 1965.
J. Med. Chem., vol. 8, Wiseman, et al., pp. 777-781 1965.
J. Med. Chem., vol. 8, McFarland, et al., pp. 781-784 1965.
Annalen der Chemie, 562, Petersen, pp. 205-229 1949.

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