Aminostyryl compound, leukotriene antagonistic composition conta

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544224, 544235, 544283, 544336, 544349, 544358, 544402, 544403, 546112, 546164, 546175, 546201, 546229, 546238, 546246, 546247, 548326, 548371, 548378, 548469, 548482, 548511, 548560, 548565, 514248, 514249, 514255, 514256, 514258, 514259, 514311, 514315, 514415, 562433, 562442, 560 37, A61K 31505, C07D23926, C07D23930, C07D23934

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047497017

ABSTRACT:
Disclosed are an aminostyryl compound represented by Formula I: ##STR1## wherein A represents a linking group having 3 to 4 chain members; B represents an unsubstituted or substituted 5 to 6-membered monocyclic type heterocyclic residue containing 1 to 2 hetero atoms, an unsubstituted or substituted condensed heterocyclic residue which contains 5 to 6-membered monocyclic type heterocycle containing 1 to 2 hetero atoms, a naphthyl group or an alkyl group having 5 to 7 carbon atoms,
a composition having leukotriene antagonism which contains an aminostyryl compound represented by Formula I as the effective ingredient, and a method of antagonizing SRS based on leukotriene antagonistic activity by employing the same.

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