Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1991-03-19
1992-09-01
Mars, Howard T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
552515, A61K 3156, C07J 4100
Patent
active
051439093
ABSTRACT:
The present invention relates to a method for the inhibition of C.sub.17-20 lyase enzyme which comprises administering to a patient in need of such inhibition, an effective amount of certain 4-amino-17-(hydroxyalkyl or dihydroxyalkyl)steroids or their esters or ethers. Certain of the aminosteroids used in the process are novel compounds.
REFERENCES:
patent: 4822528 (1989-04-01), Colombo et al.
Johnston, J. O. et al., Endocrinology, 115, 776 (1984).
Blohm Thomas R.
Gates Cynthia A.
Weintraub Philip M.
Kestler Kimberly J.
Kolano John J.
Mars Howard T.
Merrell Dow Pharmaceuticals Inc.
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